Figure 1.

Effect of leaf crude extract (LCE), hexane fraction (HF), chloroform fraction (CF), ethyl acetate fraction (EAF), residual fraction (RF), and flower crude extract (FCE) of M. sylvestris on PGE₂, PGD₂, TXB₂, and PGF_2α production in LPS-stimulated RAW 264.7 cells. Cells were treated with LPS in the absence or presence of the fractions at two concentrations (10 and 50 µg/mL). Dexamethasone (DEX) was used as positive control. After incubation, cell culture supernatants were harvested, and PGE₂, PGD₂, TXB₂, and PGF_2α production was determined. Values are expressed as mean ± SD. * p < 0.001 vs. control (LPS alone).