Table 1.

Sequences and structural properties of VIP and the VIP analogues.

Name	Amino Acides Sequence	Charge	GRAVY a	Molecular Weight
VIP1 b	HSDAVFTDNYTRLRKQMAVKKYLNSILN	+3	−0.639	3326.8
VIP2	HSKAVFTKNYTRLRKQMAVKKYLNSILN	+7	−0.668	3352.9
VIP3	HSDAVFTDNSTRLRKQMAVKKSLNSILN	+3	−0.604	3174.6
VIP4	HSDAVFTDNYTRLRKQMAVKKYLNSILT	+3	−0.539	3313.8
VIP5	HSKAVFTKNYTRLRKQMAVKKYLNSILT	+7	−0.568	3339.9
VIP6	HSDAVFTDNSTRLRKQMAVKKSLNSILT	+3	−0.504	3161.6
VIP7 c	HSDAVFTANYTRLRRQLAVRRYLAAILGRR	+6	−0.350	3545.2
VIP8 c	FTANYTRLRRQLAVRRYLAAILGRR	+7	−0.360	3035.6

^a Grand average of hydropathicity; ^b VIP1 is the natural vasoactive intestinal peptide; ^c VIP7 and VIP8 are cited from [14].