Table 2.
6 mg/ml fixed power | 18 mg/ml fixed power | 6 mg/ml adjustable power | 18 mg/ml adjustable power | Nicotine | Power | Nicotine × power | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | Mean | SD | F (P) | F (P) | F (P) | |
Puffing topography | |||||||||||
Daily puff number | 338 | 161 | 279 | 127 | 308 | 135 | 272 | 128 | 16.39 (0.001) | 2.16 (0.16) | 0.98 (0.34) |
Puff duration | 4.46 | 1.22 | 3.61 | 0.97 | 3.81 | 1.11 | 3.91 | 1.44 | 18.30 (0.001) | 1.69 (0.21) | 12.12 (0.003) |
Interpuff interval | 34.22 | 20.08 | 41.22 | 26.23 | 39.32 | 26.80 | 37.32 | 27.18 | 0.33 (0.58) | 0.04 (0.86) | 5.76 (0.03) |
Product use | |||||||||||
Daily (ml) liquid consumed | 6.19 | 3.74 | 4.63 | 2.13 | 5.79 | 3.63 | 4.79 | 2.35 | 6.25 (0.02) | 0.07 (0.80) | 0.75 (0.40) |
Voltage (wattage) | 4 (10) | – | 4 (10) | – | 4.5 (12.66) | 0.7 | 4.3 (11.56) | 0.8 | – | – | – |
Subjective effects | |||||||||||
Urge to vape | 3.20 | 1.11 | 2.40 | 0.10 | 3.00 | 0.86 | 2.45 | 0.83 | 16.74 (0.001) | 0.77 (0.39) | 1.95 (0.18) |
Strength of urges | 2.90 | 1.17 | 2.15 | 0.67 | 2.85 | 1.18 | 2.45 | 1.10 | 14.63 (0.001) | 0.91 (0.36) | 3.56 (0.08) |
Withdrawal symptoms | 9.05 | 4.56 | 7.80 | 2.59 | 7.45 | 2.91 | 6.80 | 1.36 | 4.88 (0.04) | 8.78 (0.01) | 2.51 (0.13) |
Positive effects | 50.71 | 19.82 | 62.64 | 20.30 | 63.85 | 21.58 | 63.42 | 22.25 | 2.06 (0.17) | 4.69 (0.05) | 26.48 (0.001) |
Negative effects | 15.05 | 19.49 | 22.25 | 22.75 | 11.26 | 9.66 | 14.74 | 12.84 | 3.37 (0.09) | 5.36 (0.03) | 0.38 (0.55) |
Biomarkers | |||||||||||
Salivary cotinine (ng/ml) | 250.45 | 188.23 | 402.52 | 190.00 | 274.95 | 172.81 | 405.21 | 192.80 | 17.49 (0.001) | 0.15 (0.70) | 0.12 (0.73) |
3‐HPMA (ng/mg creatinine) | 211.83 | 133.09 | 262.73 | 202.50 | 224.13 | 343.39 | 378.35 | 467.35 | 0.82 (0.38) | 0.29 (0.60) | 0.09 (0.77) |
Formate (μg/mg creatinine) | 10.52 | 8.00 | 9.62 | 7.28 | 18.01 | 23.56 | 7.61 | 7.24 | 4.58 (0.05) | 1.88 (0.19) | 6.92 (0.02) |
SD = standard deviation; 3‐HPMA = 3‐hydroxypropylmercapturic acid.