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. 2018 Sep 21;13(9):e0204000. doi: 10.1371/journal.pone.0204000

Table 2. Factors associated with adherence to hospital guidelines regarding undernutrition monitoring (second step: Re-checking prealbumin levels), department of internal medicine of the Lausanne university hospital, 2013 and 2014.

Characteristics Bivariate analysis Multivariable analysis
Unadjusted OR (95% CI) P-value Adjusted OR
(95% CI)
P-value
Admission year
    2013 1 (ref.) 1 (ref.)
    2014 0.88 (0.54–1.44) 0.61 1.07 (0.63–1.84) 0.79
Gender
    Men 1 (ref.) 1 (ref.)
    Women 0.75 (0.49–1.15) 0.19 0.72 (0.45–1.16) 0.17
Age category
    18–59 1 (ref.) 1 (ref.)
    60–79 0.71 (0.26–1.91) 0.49 0.73 (0.24–2.23) 0.58
    80+ 0.60 (0.23–1.55) 0.29 0.73 (0.25–2.18) 0.57
    p-value for trend* 0.24 0.31
Main diagnosis
    Miscellaneous 1 (ref.) 1 (ref.)
    Circulatory system diseases 1.44 (0.77–2.69) 0.25 0.90 (0.43–1.89) 0.79
    Cancer 1.92 (0.88–4.20) 0.10 0.99 (0.38–2.58) 0.98
    Digestive system diseases 1.92 (0.69–5.35) 0.21 1.89 (0.58–6.13) 0.29
    Infectious diseases 0.81 (0.35–1.86) 0.61 0.52 (0.21–1.27) 0.15
    Mental & behavioral disorder/ Nervous system disease 2.43 (1.09–5.43) 0.03 1.88 (0.80–4.42) 0.14
    Respiratory system diseases 1.28 (0.66–2.48) 0.46 0.94 (0.45–1.98) 0.87
NRS-2002 categories
    Medium (3–4) 1 (ref.) 1 (ref.)
    High (>4) 1.64 (1.02–2.65) 0.043 1.45 (0.85–2.48) 0.17
Charlson comorbidity index
    Low (CCI<2) 1 (ref.) 1 (ref.)
    High (CCI≥2) 1.71 (1.12–2.62) 0.014 1.73 (1.00–2.98) 0.050
Any nutritional management
    No 1 (ref.) 1 (ref.)
    Yes 3.90 (2.35–6.47) <0.001 3.98 (2.33–6.78) <0.001

Abbreviations: ref., reference category; CCI, Charlson comorbidity index; NRS-2002, nutrition risk screening 2002. Analyses were performed among patients with NRS-2002≥3, first-prealbumin levels<0.2 g/l and length of hospital stay ≥10 days (n = 346/439). Results are presented as OR (95% CI). Bivariate analysis performed using logistic regression in which adherence to the guideline (yes or no) was the outcome and each characteristic was the predictor; multivariable analysis performed using logistic regression adjusting for all variables in the table.

* P-values for trend are computed using orthogonal polynomial contrasts (command contrast p. of Stata).