Table 1.
Baseline characteristics of the ten cohort studies of asthma and cardiovascular diseases and all-cause mortality.
| First author, year | Location | Study design | Participant | Age | CVD event | Assessment of asthma | Duration (years) | Adjustment for covariates |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Iribarren, 200413 | USA | Retrospective | M 70047 W 81573 |
18–85 | CHD | Self-reported doctor diagnosis or inpatient admission for asthma | 27 | Age, race/ethnicity, education level, smoking status, alcohol consumption, BMI, TC, WBC, HTN, diabetes, parental history of CHD, and occupational exposures |
| Marco, 200514 | Italy | Prospective | 6031 | 20–44 | CVD and all-cause mortality | Self-reported doctor diagnosis | 7 | Age, sex and centre |
| Schanen, 200515 | USA | Prospective | 13501 | 45–64 | CVD | Self-reported doctor diagnosis | 14 | Age, sex, race/centre, HDL-C, LDL-C, SBP, hypertension medication use, smoking status, pack years, W/H ratio, diabetes diagnosis, sport score |
| Bellia, 200722 | Italy | Prospective | 1233 | ≥65 | CVD and all-cause mortality | Respiratory questionnaire | 5 | Smoking, comorbidity, and underweight |
| Onufrak, 200821 | USA | Prospective | 14567 | 45–64 | CVD | Self-reported doctor diagnosis | 13 | Age, BMI, black race, diabetes, HTN, education level, LDL-C, HDL-C, physical activity |
| Hyun, 20123 | USA | Retrospective | 7176 | - | CHD | Rochester epidemiology project | Asthma 7 Non-asthma 5–8 |
Race, diabetes, RA and IBD |
| Chung (ACS), 201412 | Taiwan | Retrospective | 38840 | ≥18 | ACS | Physicians | 16 | Age, sex, HTN, diabetes, hyperlipidemia, Stroke, heart failure, COPD and smoking |
| Chung (Stroke), 201411 | Taiwan | Retrospective | 72587 | ≥18 | Stroke | Physicians | Asthma 7.21 Non-asthma 7.35 |
Age, sex, AF, HTN, hyperlipidemia, heart failure, alcoholism, obesity, COPD, DVT, CAD |
| Matthew, 20159 | USA | Prospective | 6792 | 62 | CVD and all-cause mortality | Self-reported doctor diagnosis | 5 | Age, race, sex, TC, HDL-C, SBP, smoking, diabetes, antihypertensive and lipid-lowering medication used at baseline, BMI, family history of CVD, income |
| Yunus, 201510 | Denmark | Prospective | 94079 | 20–100 | CVD and all-cause mortality | Self-reported doctor diagnosis | 4.5 | Age, BMI, physical activity in leisure-time, education, income, alcohol consumption, smoking, SBP, DBP, TC, LDL-C, HDL-C, TG, diabetes, use of cholesterol-lowing medication, presence of diabetes |
BMI:body mass index; TC: total cholesterol; WBC: white blood cell; HTN: hypertension; CHD: coronary heart disease; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; SBP: systolic blood pressure; RA: rheumatoid arthritis; IBD: inflammatory bowel disease; COPD: chronic obstructive pulmonary disease; DVT: deep vein thrombosis; CAD: coronary artery disease;