Table 1.

Baseline characteristics of the ten cohort studies of asthma and cardiovascular diseases and all-cause mortality.

First author, year	Location	Study design	Participant	Age	CVD event	Assessment of asthma	Duration (years)	Adjustment for covariates
Iribarren, 200413	USA	Retrospective	M 70047 W 81573	18–85	CHD	Self-reported doctor diagnosis or inpatient admission for asthma	27	Age, race/ethnicity, education level, smoking status, alcohol consumption, BMI, TC, WBC, HTN, diabetes, parental history of CHD, and occupational exposures
Marco, 200514	Italy	Prospective	6031	20–44	CVD and all-cause mortality	Self-reported doctor diagnosis	7	Age, sex and centre
Schanen, 200515	USA	Prospective	13501	45–64	CVD	Self-reported doctor diagnosis	14	Age, sex, race/centre, HDL-C, LDL-C, SBP, hypertension medication use, smoking status, pack years, W/H ratio, diabetes diagnosis, sport score
Bellia, 200722	Italy	Prospective	1233	≥65	CVD and all-cause mortality	Respiratory questionnaire	5	Smoking, comorbidity, and underweight
Onufrak, 200821	USA	Prospective	14567	45–64	CVD	Self-reported doctor diagnosis	13	Age, BMI, black race, diabetes, HTN, education level, LDL-C, HDL-C, physical activity
Hyun, 20123	USA	Retrospective	7176	-	CHD	Rochester epidemiology project	Asthma 7 Non-asthma 5–8	Race, diabetes, RA and IBD
Chung (ACS), 201412	Taiwan	Retrospective	38840	≥18	ACS	Physicians	16	Age, sex, HTN, diabetes, hyperlipidemia, Stroke, heart failure, COPD and smoking
Chung (Stroke), 201411	Taiwan	Retrospective	72587	≥18	Stroke	Physicians	Asthma 7.21 Non-asthma 7.35	Age, sex, AF, HTN, hyperlipidemia, heart failure, alcoholism, obesity, COPD, DVT, CAD
Matthew, 20159	USA	Prospective	6792	62	CVD and all-cause mortality	Self-reported doctor diagnosis	5	Age, race, sex, TC, HDL-C, SBP, smoking, diabetes, antihypertensive and lipid-lowering medication used at baseline, BMI, family history of CVD, income
Yunus, 201510	Denmark	Prospective	94079	20–100	CVD and all-cause mortality	Self-reported doctor diagnosis	4.5	Age, BMI, physical activity in leisure-time, education, income, alcohol consumption, smoking, SBP, DBP, TC, LDL-C, HDL-C, TG, diabetes, use of cholesterol-lowing medication, presence of diabetes

BMI:body mass index; TC: total cholesterol; WBC: white blood cell; HTN: hypertension; CHD: coronary heart disease; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; SBP: systolic blood pressure; RA: rheumatoid arthritis; IBD: inflammatory bowel disease; COPD: chronic obstructive pulmonary disease; DVT: deep vein thrombosis; CAD: coronary artery disease;