Table 1.
Demographic and clinical characteristics of the 21 patients.
| Case | Gender | Age at diagnosis | Lentigines +/− | NMSC (SCC or BCC) | Cutaneous MM | Other skin findings | Ocular involvement | CNS |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| 1 | F | 11 y | + | BCC | − | − | Dryness | − |
| 2 | M | 9 mo | + | BCC | − | Neurofibroma | Photophobia | − |
| 3 | F | 10 y | + | BCC | − | Seborrheic keratosis | SCC, photophobia, dryness | − |
| 4 | M | 26 y | − | BCC+SCC | + | − | Photophobia, Pterygium | − |
| 5 | F | 14 y | + | BCC+SCC | + | − | Dryness, SCC | − |
| 6 | M | 1 y | + | − | − | − | − | − |
| 7 | M | 19 y | + | BCC+SCC | − | Actinic cheilitis | Photophobia, Pterygium | − |
| 8 | F | 23 | + | BCC | − | − | Pterygium | − |
| 9 | M | 6 mo | + | BCC | − | − | Photophobia | + |
| 10 | M | 6 mo | + | SCC | − | − | Photophobia | + |
| 11 | M | 1 y | + | BCC+SCC | + | Neurofibroma Trichilemmoma | Pterygium, photophobia, dryness | − |
| 12 | M | 2 mo | + | SCC | − | − | Photophobia | − |
| 13 | F | 2 y | + | BCC | − | Gingival involvement, gingivitis. | Photophobia | − |
| 14 | F | 3 y | + | BCC | − | Trichilemmoma | Photophobia | − |
| 15 | M | − | − | BCC | − | − | SCC | − |
| 16 | F | 15 y | + | BCC | − | Neurofibroma, seborrheic keratosis | Photophobia, dryness, SCC | − |
| 17 | M | − | − | SCC | − | − | − | − |
| 18 | F | 8 y | + | SCC+BCC | − | Seborrheic keratosis, trichilemmoma, | Limbal melanoma | − |
| 19 | M | Referred to KFSH at 30y | + | SCC | + | − | Photophobia | − |
| 20 | F | 2 y | + | BCC | − | Gingival involvement-pyogenic granuloma | − | − |
| 21 | F | 18 mo | + | − | − | − | Photophobia | − |
NMSC: non-melanoma skin cancer, BCC: basal cell carcinoma, SCC: squamous cell carcinoma