Table 1.
Factors associated with incident non-melanoma skin cancer (NMSC) among patients receiving bone marrow transplant (BMT) at Moffitt Cancer Center
| Variable | Overall Cohort n=3,587 n(%) |
Incident NMSC n=31 n(%) |
HR1 (95% CI |
|---|---|---|---|
| Age at BMT | 53.5 (12.9) | 57.2 (11.9) | 1.03 (1.00–1.06) |
| Mean(std) | |||
| Gender | |||
| Male | 2054 (57.3) | 22 (71.0) | 1.00 |
| Female | 1533 (42.7) | 9 (29.0) | 0.56 (0.26–1.22) |
| Race | |||
| White | 3061(85.3) | 29 (93.5) | 1.00 |
| Non white | 526 (14.7) | 2 (6.4) | 0.42 (0.10–1.79) |
| BMT type | |||
| Auto | 2205 (61.5) | 16 (51.6) | 1.00 |
| Allo | 1382 (38.5) | 15 (48.4) | 2.85 (1.36–5.96) |
| Acute GVHD skin | |||
| None (grade 0) | 482 ( 43.8) | 5 (33.3) | 1.00 |
| Grades 1–4 | 619 ( 56.2) | 10 (66.7) | 1.43 (0.49–4.20) |
| Smoking | |||
| Never | 2913 (84.7) | 7 (43.7) | 1.00 |
| Ever | 524 (15.2) | 9 (56.2) | 1.58 (0.59–4.24) |
HR=hazards ratio, CI=confidence interval, GVHD=graft versus host disease.
1
Age adjusted for all variables examined as risk factors, unadjusted for age as the risk factor.