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. 2018 May 14;10(5):751–764. doi: 10.1080/19420862.2018.1462429

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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graphic file with name kmab-10-05-1462429-g006.jpg — Predicted human PK profiles using ‘typical’ human popPK parameter estimates ( ), compared with observed (individual) dose normalized human PK data (symbols) and profiles from fitting human data for individual mAbs ( ).

Inline graphic — Predicted human PK profiles using ‘typical’ human popPK parameter estimates ( ), compared with observed (individual) dose normalized human PK data (symbols) and profiles from fitting human data for individual mAbs ( ).