Laser-cut demonstration
chips, which can be modified or redesigned
by learners. (a) Laser-cut foil chip, made from 80 mm GBC High Speed
laminator foil. The chips produced (outer dimensions 45 mm long, 15
mm wide, and 0.24 mm thick) are fitted on top of a 1 mm thick support
plate, in the mount of the lab-on-a-chip holder. (b) The first prototype
chip, showing trilaminar flow, in the chip holder. (c) A laser-cut
Y reactor chip, mounted in the acrylic glass (PMMA) holder, connected
with silicone ferrules. In this experiment the formation of calcite
precipitate is studied, as described by Chia et al.5 (d) Calcite precipitate visible in the first part of a
laser-cut serpentine mixer channel (width 100 μm, produced from
125 μm thick Leitz foil), from 0.025 M CaCl2 and
0.1 M NaHCO3 solution with syringe pumps at a flow speed
of 45 μL/min. All details of the design of the foil chips and
the PMMA holder are described in the Supporting Information.