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. 2018 Jul-Aug;23(4):45–54. doi: 10.1590/2177-6709.23.4.045-054.oar

Table 1. Summary of descriptive characteristics of included studies.

Author (year) Method MAS Subjects Control Follow-up period MAS Use Side effects summary
Type Protrusion Type n
Doff et al.16 (2010) Cephalometry Thornton Adjustable Positioner (TAP®) 79 ± 20% of maximum protrusion OSA 31 CPAP 2.3 ± 0.2 year > 6 nights/week Overbite and overjet decreased; retroclination of the upper incisors and proclination of the lower incisors; lower and total anterior facial height increased significantly; no changes in skeletal variables were found
Doff et al.10 (2012) Clinical measurements (RDC/TMD) and questionnaire Thornton Adjustable Positioner (TAP®) 76 ± 25% of maximum protrusion OSA 51 CPAP 2 months, 1 year and 2 years 6.7 ± 0.6 nights/week OA therapy results in more pain-related TMDs in the initial period of use, compared with CPAP therapy
Doff et al.17 (2013) Dental plaster study models Thornton Adjustable Positioner (TAP®) 79 ± 19% of maximum protrusion OSA 51 CPAP 2.3 ± 0.2 year 6.9 ± 0.4 nights/week Decreased overjet/overbite, anteroposterior change in the occlusion, decreased number of occlusal contact points in the posterior region
Ringqvist et al.14 (2003) Cephalometry Non- adjustable 50% of maximum protrusion OSA 27 Uvulopala-topharyn-goplasty 4.1 year (4.0 - 4.2) 6.1 nights/week Changes in vertical positions of the maxillary incisors and the mandibular incisors, posterior rotation of the mandible; overjet and overbite did not change significantly
Robertson et al.13 (2003) Cephalometry Non- adjustable 75% of maximum protrusion OSA/ snoring 100 Pre-MAS therapy 6, 12, 18, 24 and 30 months > 5-6 hours/nights 7 nights/week Changes in face height, the position of the mandible, overjet, and overbite occurred as early as 6 months. Over-eruption of the maxillary first premolars and mandibular first molars and proclination of the mandibular incisors were not evident for at least 2 years.
Tegelberg et al.15 (1999) Clinical examination (Helkimo; Eichner index of occlusal support zones) Non- adjustable 50% of maximum protrusion OSA 37 Uvulopala-topharyn-goplasty 1 year 6 nights/week Few adverse events in the stomatognathic system or other complications