| Author (year) |
Method |
MAS |
Subjects |
Control |
Follow-up period |
MAS Use |
Side effects summary |
| Type |
Protrusion |
Type |
n |
|
|
|
|
| Doff et al.16 (2010) |
Cephalometry |
Thornton Adjustable Positioner (TAP®) |
79 ± 20% of maximum protrusion |
OSA |
31 |
CPAP |
2.3 ± 0.2 year |
> 6 nights/week |
Overbite and overjet decreased; retroclination of the upper incisors and proclination of the lower incisors; lower and total anterior facial height increased significantly; no changes in skeletal variables were found |
| Doff et al.10 (2012) |
Clinical measurements (RDC/TMD) and questionnaire |
Thornton Adjustable Positioner (TAP®) |
76 ± 25% of maximum protrusion |
OSA |
51 |
CPAP |
2 months, 1 year and 2 years |
6.7 ± 0.6 nights/week |
OA therapy results in more pain-related TMDs in the initial period of use, compared with CPAP therapy |
| Doff et al.17 (2013) |
Dental plaster study models |
Thornton Adjustable Positioner (TAP®) |
79 ± 19% of maximum protrusion |
OSA |
51 |
CPAP |
2.3 ± 0.2 year |
6.9 ± 0.4 nights/week |
Decreased overjet/overbite, anteroposterior change in the occlusion, decreased number of occlusal contact points in the posterior region |
| Ringqvist et al.14 (2003) |
Cephalometry |
Non- adjustable |
50% of maximum protrusion |
OSA |
27 |
Uvulopala-topharyn-goplasty |
4.1 year (4.0 - 4.2) |
6.1 nights/week |
Changes in vertical positions of the maxillary incisors and the mandibular incisors, posterior rotation of the mandible; overjet and overbite did not change significantly |
| Robertson et al.13 (2003) |
Cephalometry |
Non- adjustable |
75% of maximum protrusion |
OSA/ snoring |
100 |
Pre-MAS therapy |
6, 12, 18, 24 and 30 months |
> 5-6 hours/nights 7 nights/week |
Changes in face height, the position of the mandible, overjet, and overbite occurred as early as 6 months. Over-eruption of the maxillary first premolars and mandibular first molars and proclination of the mandibular incisors were not evident for at least 2 years. |
| Tegelberg et al.15 (1999) |
Clinical examination (Helkimo; Eichner index of occlusal support zones) |
Non- adjustable |
50% of maximum protrusion |
OSA |
37 |
Uvulopala-topharyn-goplasty |
1 year |
6 nights/week |
Few adverse events in the stomatognathic system or other complications |
