Table 1.
Comb-push shear elastography results compared to sonographic pattern classification and Bethesda Diagnostic category for thyroid nodules.
| Classification of thyroid nodules based on sonographic and FNA findings | Sonographic pattern (N) | ||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Benign (0) | Very low suspicion (42) | Low suspicion (66) | Intermediate suspicion (37) | High suspicion (28) | |||
|
| |||||||
| Estimated risk of malignancy (%) | < 1 | < 3 | 5–10 | 10–20 | > 70–90 | ||
|
| |||||||
| Emean±SD (kPa) | |||||||
|
| |||||||
| Bethesda Diagnostic Category (N) | I (15) | 1–4 | - | 17±7 (6) | 17±10 (2) | 25±6 (2) | 24±12 (5) |
| II (112) | 0–3 | - | 29±17 (32) | 30±18 (53) | 26±18 (20) | 40±19 (7) | |
| III (1) | 5–15 | - | - | - | 12 (1) | - | |
| IV (20) | 15–30 | - | 20±14 (4) | 26±13 (8) | 19±3 (4) | 15±4 (4) | |
| V (3) | 60–75 | - | - | 35±8 (2) | 63 (1) | - | |
| VI (22) | 97–99 | - | - | 59 (1) | 62±22 (9) | 73±17 (12) | |
|
| |||||||
| Emax±SD (kPa) | |||||||
|
| |||||||
| Bethesda Diagnostic Category (N) | I (15) | 1–4 | - | 44±31 (6) | 40±30 (2) | 47±10 (2) | 60±31 (5) |
| II (112) | 0–3 | - | 58±35 (32) | 60±36 (53) | 57±54 (20) | 94±48 (7) | |
| III (1) | 5–15 | - | - | - | 23 (1) | - | |
| IV (20) | 15–30 | - | 35±24 (4) | 43±18 (8) | 46±28 (4) | 27±4 (4) | |
| V (3) | 60–75 | - | - | 73±29 (2) | 145 (1) | - | |
| VI (22) | 97–99 | - | - | 114 (1) | 147±49 (9) | 164±31 (12) | |
(N) indicates statistical frequency; Emean, mean elasticity; Emax, maximum elasticity.
I - Nondiagnostic or Unsatisfactory
II – Benign
III - Atypia of Undetermined Significance or Follicular Lesion of Undetermined Significance
IV - Follicular Neoplasm or Suspicious for a Follicular Neoplasm
V - Suspicious for Malignancy
VI - Malignant