Table 5.
Zero-Inflated Poisson Regression Models of Summed Marijuana Use and Alcohol Use (≥5 Drinks) Frequency Categories by Individual Subject Intercepts and Slopes from Multilevel Linear Models (MLM) of Orbital Frontal Cortex (OFC) Volume Residuals and OFC Thickness by Time-Varying CDI-C Anhedonia (N=135)
| Estimate | SE | t | p | |
|---|---|---|---|---|
| Zero-inflated: marijuana /alcohol abstinence | ||||
| Intercept | 8.1699 | 5.2383 | 1.56 | 0.1188 |
| Intercept from MLM of OFC volume residuals | −0.2889 | 0.2199 | −1.31 | 0.1888 |
| Caucasian race | 1.2379 | 0.8548 | 1.45 | 0.1476 |
| Male gender | −0.3746 | 0.7803 | −0.48 | 0.6312 |
| Age at last assessment | −0.5740 | 0.3373 | −1.70 | 0.0888 |
| Continuous: frequency of use | ||||
| Intercept | −3.0915 | 2.4523 | −1.26 | 0.2074 |
| Intercept from MLM of OFC volume residuals | −0.2017 | 0.0696 | −2.90 | 0.0038 |
| Caucasian race | −0.0951 | 0.3401 | −0.28 | 0.7797 |
| Male gender | 0.2691 | 0.3288 | 0.82 | 0.4131 |
| Age at last assessment | 0.1906 | 0.1513 | 1.26 | 0.2076 |
|
| ||||
| Zero-inflated: marijuana /alcohol abstinence | ||||
| Intercept | 8.9732 | 4.7298 | 1.90 | 0.0578 |
| Slope from MLM of OFC volume residuals | 8.8264 | 4.7813 | 1.85 | 0.0649 |
| Caucasian race | 0.3490 | 0.6779 | 0.51 | 0.6067 |
| Male gender | 0.0255 | 0.7276 | 0.04 | 0.9720 |
| Age at last assessment | −0.5352 | 0.2998 | −1.79 | 0.0743 |
| Continuous: frequency of use | ||||
| Intercept | −2.9693 | 2.3376 | −1.27 | 0.2040 |
| Slope from MLM of OFC volume residuals | 1.3176 | 1.5667 | 0.84 | 0.4003 |
| Caucasian race | −0.5484 | 0.2978 | −1.84 | 0.0655 |
| Male gender | 0.5180 | 0.3044 | 1.70 | 0.0888 |
| Age at last assessment | 0.2024 | 0.1418 | 1.43 | 0.1535 |
|
| ||||
| Zero-inflated: marijuana/alcohol abstinence | ||||
| Intercept | 21.3707 | 12.6235 | 1.69 | 0.0905 |
| Intercept from MLM of OFC thickness | −1.3092 | 1.2100 | −1.08 | 0.2793 |
| Caucasian race | 0.4801 | 0.9149 | 0.52 | 0.5997 |
| Male gender | −0.7338 | 1.0460 | −0.70 | 0.4830 |
| Age at last assessment | −0.5013 | 0.4553 | −1.10 | 0.2709 |
| Continuous: frequency of use | ||||
| Intercept | 11.8839 | 4.1470 | 2.87 | 0.0042 |
| Intercept from MLM of OFC thickness | −1.5213 | 0.3699 | −4.11 | <0.0001 |
| Caucasian race | −0.5022 | 0.2995 | −1.68 | 0.0936 |
| Male gender | 0.2242 | 0.3327 | 0.67 | 0.5004 |
| Age at last assessment | 0.2862 | 0.1570 | 1.82 | 0.0683 |
|
| ||||
| Zero-inflated: marijuana /alcohol abstinence | ||||
| Intercept | −1525.124 | 21.6553 | −70.043 | <0.0001 |
| Slope from MLM of OFC thickness | −13151 | 7.6639 | −1716.0 | <0.0001 |
| Caucasian race | 186.4047 | 364.0409 | 0.51 | 0.6086 |
| Male gender | 30.3424 | 76.6287 | 0.40 | 0.6921 |
| Age at last assessment | −54.3685 | 24.3988 | −2.23 | 0.0259 |
| Continuous: frequency of use | ||||
| Intercept | −16.5681 | 2.7172 | −6.10 | <0.0001 |
| Slope from MLM of OFC thickness | −64.1517 | 13.0766 | −4.91 | <0.0001 |
| Caucasian race | −0.4468 | 0.2225 | −2.01 | 0.0446 |
| Male gender | 0.5044 | 0.2202 | 2.29 | 0.0220 |
| Age at last assessment | 0.3818 | 0.1090 | 3.50 | 0.0005 |