Table 2.
Cycle and embryologic outcomes by male factor
| Sperm concentration (M/ml) | Group A (< 1 M/ml) | Group B (1 - < 5 M/ml) | Group C (5 - < 15 M/ml) | Group D (≥ 15 M/ml) |
|---|---|---|---|---|
| Number of cycles | 260 | 216 | 265 | 525 |
| Number of injected oocytes, mean ± SD | 6.8 ± 4.4 | 6.5 ± 4.0 | 6.4 ± 4.1 | 6.9 ± 4.2 |
| Fertilization rate, median (IQR) | 66.7 (40.0–80.0)*** | 71.4 (50.0–90.1) | 71.4 (55.5–90.0) | 75.0 (57.1–90.2) |
| Rate of blastocyst formation, median (IQR) | 50.0 (33.3–66.3)* | 50.0 (36.4–70.0) | 50.0 (37.6–71.4) | 55.6 (40.0–75.0) |
| Rate of top quality blastocyst, median (IQR) | 0.0 (0.0–33.3) | 0.0 (0.0–30.0) | 0.0 (0.0–20.0) | 0.0 (0.0–25.0) |
| Rate of blastocyst in day V, median (IQR) | 66.7 (33.3–100) | 50.0 (33.3–85.8)* | 50.0 (31.2–84.0)** | 66.7 (40.0–100) |
| Number of transferred embryos, mean ± SD | 1.7 ± 0.6 | 1.7 ± 0.6 | 1.7 ± 0.7 | 1.6 ± 0.7 |
| Number of transfer day V (%) | 86 (33.1%)* | 78 (36.1%) | 93 (35.1%)* | 237 (45.1%) |
| Number of frozen embryos, mean ± SD | 1.3 ± 2.0 | 1.6 ± 2.1 | 1.6 ± 2.1 | 1.9 ± 2.3 |
| Number of transfer (%) | 165 (63.4%) | 141 (65.2%) | 171 (64.5%) | 351 (66.8%) |
| Ongoing Pregnancy, OR (<IC95%) | 1.1 (0.7–1.8) | 0.9 (0.5–1.5) | 0.7 (0.4–1.1) | 1 |
* P < 0.05, ** P < 0.01, *** P < 0.001 (adjusted for confounders) vs group D. M/ml million per milliliter, SD standard deviation, OR odd ratio, IQR Interquartile Range