Table 1.
Characteristics and clinical outcome of couples with unexplained infertility allocated to different reproductive treatments
| IUI | IVF | ICSI | ||
|---|---|---|---|---|
| Ejaculated | Surgically retrieved | |||
| No. of patients | 354 | 31 | 343 | 34 |
| No. of cycles | 1133 | 63 | 796 | 58 |
| Male age (mean ± SD) | 40.7 ± 6 | 39.4 ± 5 | 39.8 ± 6 | 45.6 ± 11 |
| Female age (mean ± SD) | 37.5 ± 5 | 36.3 ± 4 | 37.6 ± 4 | 37.4 ± 4 |
| Fertilization (%) | – | 425/696 (61.1)a | 5210/7139 (73.0)b | 354/533 (66.4)c |
| Clinical pregnancy (%) | 20/1133 (1.8)d | 8/63 (12.7)e | 149/796 (18.7)f | 20/58 (31.0)g |
| Implantation (%) | – | 11/151 (7.3)h | 178/1650 (10.8)i | 25/95 (26.3)j |
| Delivery and ongoing (%) | 14/1133 (1.2)k | 6/63 (9.5)l | 105/796 (13.2)m | 18/58 (31.0)n |
a vs b, c: χ2, 2 × 3, 2 df, effect of insemination method on fertilization rates, P < 0.00001; d vs e, f, g: χ2, 2 × 4, 3 df, effect of insemination method on clinical pregnancy rates, P < 0.00001; h vs i, j: χ2, 2 × 3, 2 df, effect of insemination method on implantation rates, P < 0.00001; k vs l, m, n: χ2, 2 × 4, 3 df, effect of insemination method on delivery and ongoing pregnancy rates, P < 0.00001