Table 4.
Disease and bio-function predicted by IPA analysis
| Categories | Functions | Diseases or functions annotation | P value | Predicted activation state | Activation z score | Molecules |
|---|---|---|---|---|---|---|
| Organ development | CYP19A1, PRLR, I | |||||
| Reproductive system | Growth | Growth of genital organ | 0.0000968 | 1.919 | GFBP7, CCND2, B | |
| Development and function | MP15, INHA | |||||
| Organ morphology | ||||||
| Reproductive system | ZP3, PABPC1L, Z | |||||
| Development and function | Quantity | Quantity of oocytes | 0.0000924 | 1.969 | P2, BMP15 | |
| Tissue morphology | ||||||
| Embryonic development | ||||||
| Organ development | ZP3, CYP19A1, A | |||||
| Organismal development | Development | Development of ovary | 0.00000495 | 1.99 | MHR2, CCND2, P | |
| reproductive system | TPRN, ZP2, BMP1 | |||||
| Development and function | 5, INHA | |||||
| Tissue development | ||||||
| Embryonic development | ||||||
| Organ development | ZP3, CYP19A1, C | |||||
| Organismal development | Folliculogenesis | Folliculogenesis | 0.0000106 | 1.99 | CND2, PTPRN, ZP | |
| Reproductive system | 2, BMP15, INHA | |||||
| Development and function | ||||||
| Tissue development | ||||||
| Organ morphology | ||||||
| Reproductive system | ZP3, CYP19A1, P | |||||
| Development and function | Quantity | Quantity of germ cells | 0.0000997 | Increased | 2.409 | ABPC1L, ZP2, BM |
| Tissue morphology | P15, INHA, CHD5 |