Table 1.
The effect of cisplatin treatment on DRG neuron subclass expression in adults. Total number of sensory DRG neurons expressing CGRP, IB4, NF200 or TrkA were determined in experimental groups vehicle and cisplatin treat at P45 of age. (*P < 0.05 Unpaired T test; vehicle = 5, cisplatin n = 5)
| Vehicle |
Cisplatin |
|
|---|---|---|
| % Total Sensory Neuron Number (Mean ± SEM) | % Total Sensory Neuron Number (Mean ± SEM) | |
| CGRP | 30.88 ± 1.24 | 30.71 ± 1.63 |
| IB4 | 41.88 ± 3.46 | 47.39 ± 1.79 |
| NF200 | 41.05 ± 2.59 | 41.12 ± 3.49 |
| TrkA | 37.20 ± 2.09 | 49.59 ± 3.67* |