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. 2018 Sep 21;9:238. doi: 10.1186/s13287-018-0984-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Proposed effects of placental mesenchymal stem cells (pMSCs) on modifying negative impact of glucose on endothelial cell functions. pMSCs prevent endothelial cell injury and apoptosis from glucose and reverse inhibitory effects of glucose on endothelial cell survival, proliferation, migration, and angiogenesis. pMSCs also reduce stimulatory effects of glucose on endothelial cell permeability and monocyte infiltration through endothelial cells