Table 2.

Subgroup analysis for the need for transfusion

Subgroup	No. trials	RR (95% CI)	P value	I2 (%)	Test of interaction, P
Risk of bias
Low	4	0.60 (0.38, 0.95)	0.028	35.5	0.047
Unclear/high	3	0.50 (0.21, 1.16)	0.105	0
Dose of TXA
Low	4	0.60 (0.38, 0.93)	0.014	34.1	0.125
High	3	0.50 (0.16, 0.84)	0.023	0
Transfusion protocol
Strict	3	0.43 (0.18, 1.05)	0.064	0	0.043
Loose	4	0.63 (0.40, 0.98)	0.041	14.5