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. 2018 Sep 21;18:909. doi: 10.1186/s12885-018-4822-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Correlation between serum MMP-9 value and Miller-Payne (MP) grades. MMP-9 change after NAC was significantly correlated to response to NAC. The mean absolute changes (ng/ml) in serum MMP-9 were − 88.30 ± 286.40, 47.70 ± 188.60 and 133.00 ± 190.40 in patients with a poor response (MP 2/1), a partial response (MP 3) and an ideal response (MP 5/4), respectively. ***P < 0.001, **P < 0.01, *P < 0.05