Fig. 5.

The function of KA receptors in cultured insular cortex neurons from Fmr1 WT and Fmr1 KO mice. a, b, Typical traces of the KA produced inward current caused by puff perfusion of KA (10 μM) for 100 ms at 15 psi pressure with PTX (100 μM), AP-5 (50 μM) and GYKI53655 (100 μM) in cultured insular cortex neurons from Fmr1 WT (A) and Fmr1 KO mice (B). c, Avaraged data showing that there was no significant difference in KA-induced inward currents between cultured neurons from Fmr1 WT and Fmr1 KO mice (n = 6 in 6 Fmr1 WT, n = 6 in 5 Fmr1 KO mice)