Table 2.
Multiple regression analysis of ABI in T2DM patients
| Analysis | Univariate
|
Multivariate
|
||
|---|---|---|---|---|
| β | P-value | β | P-value | |
| Age (years) | 0.2247 | 0.08956 | ||
| Sex (men) | −0.1128 | 0.31257 | ||
| BMI (kg/m2) | −0.3395 | 0.00343* | −0.2139 | 0.07914 |
| HbA1c (%) | −0.4216 | 0.00287* | −0.2969 | 0.04972* |
| UA (mg/dL) | 0.0219 | 0.56475 | ||
| TC (mg/dL) | −0.1869 | 0.11239 | ||
| HDL (mg/dL) | 0.2418 | 0.09774 | ||
| LDL (mg/dL) | −0.3125 | 0.00963* | −0.2537 | 0.05649 |
| CRP (mg/dL) | −0.4129 | 0.00166* | −0.3218 | 0.01024* |
| IL-6 (pg/mL) | 0.1433 | 0.13207 | ||
| MCP-1 (pg/mL) | −0.3127 | 0.01236 | −0.2027 | 0.08961 |
| sE-selectin (ng/mL) | −0.2686 | 0.04423* | −0.1366 | 0.09897 |
| sVCAM-1 (ng/mL) | −0.2762 | 0.04124* | −0.1966 | 0.09567 |
| PDMP (U/mL) | −0.5029 | 0.00012* | −0.3984 | 0.01356* |
| PAI-1 (ng/mL) | −0.5244 | 0.01029* | −0.4313 | 0.01129* |
| Adiponectin (μg/mL) | 0.3235 | 0.02867* | 0.2047 | 0.09833 |
Note:
*
P<0.05.
Abbreviations: ABI, ankle brachial pressure index; BMI, body mass index; CRP, C-reactive protein; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; IL-6, interleukin-6; LDL, low-density lipoprotein; MCP-1, monocyte chemoattractant protein-1; PAI-1, plasminogen activator inhibitor-1; PDMP, platelet-derived microparticle; sE-selectin, soluble E-selectin; sVCAM-1, soluble vascular cell adhesion molecule 1; T2DM, type 2 diabetes mellitus; TC, total cholesterol; UA, uric acid.