Table 2.
Comparison of treatment parameters between responders and nonresponders with statistical analysis
| Characteristics | Responders
|
Nonresponders
|
After treatment–before treatment
|
|||
|---|---|---|---|---|---|---|
| Pre-t/t | Post-t/t | Pre-t/t | Post-t/t | Z (normal score) | Asymptotic significance (two-tailed; p-value) | |
| Mean duration of treatment (days) | 6.7±2.1 | 9.5±4.8 | ||||
| Serum creatinine (mg/dL) | 3.26±0.48 | 1.28±0.14 | 4.33±0.21 | 4.87±0.28 | −4.111 | <0.001 |
| Creatinine clearance (mL/min) | 21.7±4.1 | 67.7±12.1 | 15.3±2.6 | 12.6±1.5 | −4.107 | <0.001 |
| Urine output (mL/day) | 583±41.1 | 1163±105 | 468±51.9 | 223±44 | −4.109 | <0.001 |
| MAP (mm of Hg) | 79.2±2.94 | 93.9±2.34 | 70.2±0.70 | 85.5±8.12 | −4.133 | <0.001 |
| Serum sodium (mEq/L) | 125±2.01 | 132.3±1.39 | 123.8±1.80 | 123.5±2.20 | −4.163 | <0.001 |
| GFR in cirrhosis (mL/min/1.73 m2) | 14.1±2.2 | 40.5±7.2 | 9.92±1.0 | 9.49±0.8 | −3.591 | <0.001 |
Note: Data presented as mean ± SD.
Abbreviations: GFR, glomerular filtration rate; MAP, mean arterial pressure; t/t, treatment.