Table 2.

Fatal adverse events by specific type

Adverse events	Events on the MTA arms	Events on control arms
Death not otherwise specified	628,30,33	132
Hepatic failure	1025,27–29,32,33	525,27
Myocardial infarction/ischemia	329,31	132
Upper gastrointestinal hemorrhage	330	230
Intracranial hemorrhage	332	0
Encephalopathy	328	0
Renal failure	330,33	130
Pulmonary infection, pneumonitis	325,27,30	125
Gastric perforation	130	0
Febrile neutropenia	0	129
Thrombosis or embolism	0	229,33
Acidosis	128	0
Cerebral edema	128	0
Cerebrovascular accident	130	0
Interstitial lung disease	130	0
Peritonitis	227,30	0
Respiratory failure	130	130
Multiorgan failure	133	130
Sepsis, septic shock	225,33	133

Abbreviation: MTA, molecular targeted agent.