Table 2. Antimicrobial (MIC and MBC) and hemolytic (HC50) activity, and relative safety (TI) of DRS-CA-1, DRS-DU-1, DP-1, and DP-2.
Data represent the mean of ≥3 determinations.
| Strains | MIC/MBC (µM) | |||
|---|---|---|---|---|
| DRS-CA-1 | DRS-DU-1 | DP-1 | DP-2 | |
| S. aureus | 4/16 | 4/16 | 64/128 | 8/8 |
| MRSA | 8/32 | 4/16 | 128/128 | 16/16 |
| E. faecalis | 128/256 | 64/128 | 256/>512 | 32/128 |
| E. coli | 4/16 | 4/16 | 64/128 | 4/8 |
| P. aeruginosa | 8/32 | 4/16 | 128/256 | 8/16 |
| K. pneumoniae | 8/128 | 4/64 | 128/>512 | 32/256 |
| C. albicans | 4/16 | 4/16 | 32/64 | 4/8 |
| Horse Erythrocytes (HC50) | 114.7 | 216.6 | >512 | >512 |
| TI (overall) | 21.73 | 54.15 | 13.93 | 147.13 |