Table 4.
Healthcare utilization and costs during 6 months after review of review family history reports and whole genome sequencing reports, if applicable.*
| Mean Counts (SD) |
Mean Cost, USD |
Difference in Mean Costs, USD (95% CI) |
p | |||
|---|---|---|---|---|---|---|
| Cardiology Cohort | Control (n=51) | WGS (n=49) | Control (n=51) | WGS (n=49) | ||
| Visits | 7.2 (7.5) | 7.8 (6.5) | 1347 | 1344 | −3 (−517 to 488) | 0.504 |
| Labs, outpatient care | 6.9 (6.8) | 9.5 (15.5) | 109 | 137 | 28 (−39 to 132) | 0.388 |
| Imaging tests, outpatient care | 2.1 (1.9) | 2.1 (2.2) | 638 | 696 | 58 (−300 to 445) | 0.385 |
| Cardiology tests, outpatient care | 3.2 (1.7) | 3.1 (1.9) | 188 | 192 | 4 (−42 to 52) | 0.473 |
| Other outpatient procedures | † | † | 1489 | 2265 | 776 (−1401 to 3091) | 0.337 |
| Hospitalizations | 0.3 (0.8) | 0.2 (0.4) | 4978 | 2717 | −2261 (−7283 to 2459) | 0.280 |
| Medications | 4.5 (2.6) | 5.2 (3.1) | 437 | 468 | 31 (−211 to 292) | 0.389 |
| Medical equipment | † | † | 39 | 20 | −19 (−65 to 17) | 0.318 |
| Visit co-pays | † | † | 319 | 208 | −111 (−409 to 126) | 0.516 |
| Patient procedural co-pays | † | † | 75 | 46 | −29 (−84 to 23) | 0.627 |
| Additional out-of-pocket | † | † | 51 | 15 | −36 (−94 to 7) | 0.406 |
| Total, Cardiology | 9670 | 8109 | −1560 (−7558 to 3866) | 0.357 | ||
| Excluding hospitalizations | 4692 | 5392 | 700 (−1634 to 3440) | 0.393 | ||
| Primary Care Cohort | Control (n=50) | WGS (n=50) | Control (n=50) | WGS (n=50) | ||
| Visits | 6.9 (7.4) | 8.4 (8.7) | 1347 | 1581 | 234 (−317 to 759) | 0.403 |
| Labs, outpatient care | 4.4 (4.8) | 5.5 (5.9) | 66 | 96 | 30 (−9 to 76) | 0.410 |
| Imaging tests, outpatient care | 0.9 (1.5) | 1.0 (1.4) | 149 | 227 | 78 (−40 to 205) | 0.586 |
| Cardiology tests, outpatient care | 0.4 (0.6) | 0.5 (0.9) | 49 | 52 | 3 (−28 to 39) | 0.579 |
| Other outpatient procedures | † | † | 540 | 625 | 85 (−460 to 634) | 0.787 |
| Hospitalizations | 0.0 (0.2) | 0.0 (0.1) | 142 | 449 | 307 (−473 to 1211) | 0.811 |
| Medications | 2.0 (2.1) | 1.8 (1.9) | 159 | 157 | −2 (−108 to 99) | 0.674 |
| Medical equipment | † | † | 7 | 4 | −3 (−24 to 12) | 0.645 |
| Visit co-pays | † | † | 357 | 317 | −41 (−518 to 287) | 0.424 |
| Patient procedural co-pays | † | † | 110 | 150 | 40 (−124 to 231) | 0.370 |
| Additional out-of-pocket | † | † | 62 | 11 | −52 (−183 to 17) | 0.371 |
| Total, Primary Care | 2989 | 3670 | 681 (−884 to 2171) | 0.699 | ||
| Excluding hospitalizations | 2847 | 3221 | 374 (−991 to 1570) | 0.577 | ||
*
Cardiology patients also received a review of findings from prior genetic testing for their cardiomyopathy diagnoses.
†
Counts data were not collected for these items.