Skip to main content
. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Exp Neurol. 2018 Aug 1;309:91–106. doi: 10.1016/j.expneurol.2018.07.016

Figure 4. Expression levels of TLR-3 mRNA in two series of AD and non-demented brain samples.

Figure 4.

Quantitative real time reverse transcription-polymerase chain reaction (qPCR) analyses of TLR-3 mRNA expression in middle temporal gyrus of series of low plaque ND cases (n=18) and AD cases (n=24) (A) and a series of ND-LP (n=11), ND-HP (n=13) and AD cases (n=12) (D) demonstrate significant increase in TLR-3 mRNA in AD cases. Correlation analyses of TLR-3 mRNA values from both series with corresponding plaque and tangle ranking scores showed significant correlation with plaque scores (B and D) and tangle scores for first series (C), but not for second series of brain samples.