Table 2.
Effect of Calpurnia aurea leaf extract on oral glucose tolerance in normal mice.
Group | Blood glucose level (mg/dl) | |||
---|---|---|---|---|
0 min | 30 min | 60 min | 120 min | |
DW 10 ml/kg | 87.06 ± 8.25 | 202.95 ± 15.84β3 | 142.17 ± 15.66β1 µ1 | 112.45 ± 13.29µ3 |
CALE 100 mg/kg | 85.83 ± 8.55 | 199.50 ± 15.22β3 | 138.06 ± 16.56β1 µ1 | 84.33 ± 6.94µ3 |
CALE 200 mg/kg | 86.17 ± 5.87 | 213.00 ± 7.51β3 | 137.00 ± 9.01β2 µ3 | 93.50 ± 5.98µ3 |
CALE 400 mg/kg | 77.61 ± 7.23 | 211.72 ± 20.84β3 | 137.61 ± 14.28β1 µ2 | 81.94 ± 4.18µ3 |
GLC 5 mg/kg | 81.44 ± 1.24 | 180.72 ± 8.75β3 | 82.83 ± 5.43a1 µ3 | 61.78 ± 8.59a3 c1 µ3 |
Each value represents mean ± SEM; n=6 for each treatment. aCompared to the negative control, ccompared to CALE 200mg/kg, βcompared to baseline blood glucose level, and µcompared to the blood glucose level at 30 minute. 1p < 0.05, 2p < 0.01, and 3p < 0.001. CALE = Calpurnia aurea leaf extract, DW = distilled water, and GLC = glibenclamide. Time refers to time after oral glucose loading.