Table 5.
Group | Body weight (g) | |||
---|---|---|---|---|
Before induction of Diabetes | Baseline | 7th day of treatment | 14th day of treatment | |
Diabetic control | 28.67 ± 0.95 | 26.77 ± 0.89 | 23.88 ± 1.24n2 | 20.88 ± 1.15n3 β2 |
CALE 100 mg/kg | 28.83 ± 1.09 | 27.98 ± 0.95 | 25.07 ± 1.06n1 | 23.78 ± 0.86n3 β1 |
CALE 200 mg/kg | 28.83 ± 0.91 | 26.82 ± 1.18 | 24.83 ± 0.98n1 | 22.97 ± 0.76n3 β1 |
CALE 400 mg/kg | 28.75 ± 0.96 | 27.70 ± 0.99 | 25.00 ± 1.02n1 | 23.25 ± 1.16n3 β1 |
GLC 5 mg/kg | 28.75 ± 0.48 | 26.07 ± 0.73 | 25.95 ± 0.71 | 26.53 ± 0.72a2 |
Normal control | 29.00 ± 0.47 | 29.45 ± 0.36 | 30.03 ± 0.53 | 30.70 ± 0.59 |
Each value represents mean ± SEM; n=6 for each group. aCompared to the diabetic control, ncompared to the normal control, and βcompared to baseline body weight. 1p < 0.05, 2p < 0.01, and 3p < 0.001. CALE = Calpurnia aurea leaf extract and GLC = glibenclamide.