TABLE 2.

Haplotypes of POLN gene associated with the breast cancer phenotype. SNP reference IDs marked with * are missense mutations.

SNPs: rs9328764* rs2353552					SNPs rs10011549* rs11937432
Haplotype Effect Model: additive					Haplotype Effect Model: additive
global-stat = 6.83406, df = 2, p-val = 0.03281					global-stat = 6.3784, df = 2, p-val = 0.0412
Haplotype-specific Scores					Haplotype-specific Scores
loc-1	loc-2	Hap-Freq	Hap-Score	p-val	loc-1	loc-2	Hap-Freq	Hap-Score	p-val
A	C	0.12	−2.36	0.02	A	T	0.07	−2.37	0.02
G	A	0.12	−0.83	0.41	G	T	0.05	−0.73	0.46
G	C	0.76	2.38	0.02	A	C	0.88	2.3	0.02
SNPs: rs9328764* rs11937432					SNPs rs10011549* rs11937432
Haplotype Effect Model: additive					Haplotype Effect Model: recessive
global-stat = 7.92266, df = 3, p-val = 0.04764					global-stat = 7.99672, df = 3, p-val = 0.04608
Haplotype-specific Scores					Haplotype-specific Scores
loc-1	loc-2	Hap-Freq	Hap-Score	p-val	loc-1	loc-2	Hap-Freq	Hap-Score	p-val
A	A	0.06	−2.45	0.01	G	T	0.05	−1.66	0.1
G	A	0.05	−0.83	0.41	A	T	0.07	−1.48	0.14
A	G	0.88	2.39	0.02	A	C	0.88	2.15	0.03
SNPs rs9328764* rs11937432					SNPs rs10018786* rs2353552
Haplotype Effect Model: recessive					Haplotype Effect Model: additive
global-stat = 8.03298, df = 3, p-val = 0.04534					global-stat = 6.21471, df = 2, p-val = 0.04472
Haplotype-specific Scores					Haplotype-specific Scores
loc-1	loc-2	Hap-Freq	Hap-Score	p-val	loc-1	loc-2	Hap-Freq	Hap-Score	p-val
G	A	0.05	−1.74	0.08	G	C	0.12	−2.23	0.03
A	A	0.06	−1.1	0.27	T	A	0.12	−0.83	0.41
A	G	0.88	2.27	0.02	T	C	0.76	2.29	0.02