Table 2.

CGM Variables by Groups

CGM Sensor Glucose	HC N=22	CFNG N=23	CFAG N=42	CFRD N=23	p-value
Average (mg/dl)	98 (1.6)	106 (2.4)	109 (1.9)	118 (4.5)	<.001*
Maximum (mg/dl)	142 (4.2)	195 (5.9)	213 (8.8)	227 (11.7)	<.001†
Minimum (mg/dl)	64 (1.8)	64 (2.8)	63 (2.0)	64 (2.9)	0.946
Average AUC	1.4 ×105 (2.2 ×103)	1.5 ×105 (3.4×103)	1.6 ×105 (2.8 ×103)	1.7 ×105 (6.5 ×103)	<.001*
AUC >98 mg/dl	8.1 ×103 (1.3 ×103)	1.9 ×104 (2.2 ×103)	2.2 ×104 (2.3 ×103)	3.3 ×104 (6.0 ×103)	<.001*
# Excursions >140/day	0.5 (0.2)	2.5 (0.3)	2.3 (0.2)	3.1 (0.2)	<.001‡
# Excursions >200/day	0.0 (0.0)	0.2 (0.1)	0.4 (0.1)	0.6 (0.2)	0.009§
% time >140 mg/dl	0.6 (0.3)	7.4 (1.2)	9.5 (1.7)	14.3 (3.2)	<.001†
% time >200 mg/dl	0.0 (0.0)	0.2 (0.1)	9.5 (1.6)	15.0 (3.8)	0.125
% time <70 mg/dl	1.9 (0.6)	3.2 (1.3)	2.1 (0.5)	2.0 (0.8)	0.655
% time <60 mg/dl	0.3 (0.2)	1.6 (1.0)	0.6 (0.3)	0.6 (0.3)	0.306
Standard deviation	12 (0.6)	21 (0.9)	22.2 (1.3)	25.4 (2.0)	<.001†
MAGE	25 (1.5)	48 (2.7)	54.0 (3.6)	61.5 (5.9)	<.001†

Data presented as Mean (SE); AUC >98 mg/dl is the AUC above the average sensor glucose in HCs.

CGM=continuous glucose monitoring; HC=healthy controls; CFNG=cystic fibrosis normal glycemia; CFAG=cystic fibrosis abnormal glycemia; CFRD=cystic fibrosis related diabetes; AUC = area under the curve; MAGE = mean amplitude of glycemic excursions

^*CFRD different from all other groups, HC different from CFAG and CFRD.

^†CFRD different from CFNG, HC different from all other groups.

^‡CFRD different from CFAG, HC different from all groups.

^§CFRD different from CFNG, HC different from CFAG and CFRD