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. 2017 Sep 19;22(9):1573. doi: 10.3390/molecules22091573

Table 4.

SAR for the antimycobacterial activity.

Strain Improving Activity Decreasing Activity
M. tuberculosis H, 5-Br, 5-CH3O, 5-t-Bu, 3-Cl 5-Cl, 5-NO2, 3,5-I2
M. avium H, 5-Cl, 5-Br, 5-I, 5-CH3O, 5-t-Bu, 3-Cl 5-F, 5-NO2, 5-CH3, 5-OH, 3-I-5-Cl, 5-NO2-furylidene
M. kansasii H, 5-Cl, 5-Br, 5-CH3O, 5-t-Bu, 3-Cl 5-F, 5-NO2, 5-CH3, 3,5-X2, 3-X-5-Cl, 5-NO2-furylidene