Table 1.
Selectivity profile of 5 against a variety of MMPs 1 [43].
| MMP-1 | MMP-2 | MMP-3 | MMP-7 | MMP-8 | MMP-9 | MMP-12 | MMP-14 |
|---|---|---|---|---|---|---|---|
| 100% | 100% | 100% | 68% | 97% | 100% | 91% | 100% |
1 Remaining enzymatic activity at 10 µM inhibitor concentration.
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