Table 2.

Cys-loop motif sequences present in the nAChR subunits of S. haematobium, S. mansoni and S. japonicum.

Schistosome Species	nAChR	Cys-Loop Sequence
S. haematobium	AAR84357	CNIDILWFPFDEQSC
	AAR84358	CDIEVNWFPFDSQNC
	AAX59989	CQVEITYFPFDSQVC
	A_01761	CSVDIKYFPFDRQKC
	A_06497	CPLDVSFFPFDYQTC
	A_02378	CPVKIKYFPYDKQVC
S. mansoni	AAR84362	CDIEVNWFPFDSQNC
	Smp_139330	CDIEVNWFPFDSQNC
	AAR84361	CNIDILWFPFDEQSC
	Smp_031680	CNIDILWFPFDEQSC
	Smp_197600	CKIDITYFPFDDQSC
	Smp_157790	CKIDIKSFPFDEQTC
	Smp_132070.1	CPIDIKNFPFDYQHC
	Smp_132070.2	CPIDIKNFPFDYQHC
	Smp_012000	CPLDVSFFPFDYQTC
	Smp_142690	CQVEITYFPFDSQVC
	Smp_037960	CEVEITYFPFDTQIC
	Smp_176310	CPVKIKYFPYDKQVC
	Smp_180570	CQVDITLFPFDQQNC
S. japonicum	Sjp_0034800	CNVDVLYFPFDHQLC
	Sjp_0131150	CPLDVSFFPFDYQTC
	Sjp_0082390	CDIEVNWFPFDSQNC

Note: The Cys-loop sequence is shown with the cysteine residues and conserved FP-D-Q highlighted in black shading while gray shading indicates conserved residues.