. 2018 Sep 7;9(18):5527–5533. doi: 10.1021/acs.jpclett.8b01877

CHOL^a.

	DPPC/DLiPC/CHOL			DPPC/DOPC/CHOL
		w/o flip-flop			w/o flip-flop
	w/flip-flop	fb3.5	fb1.6	w/flip-flop	fb3.5	fb1.6
average APL (nm²)^b	0.736	0.737	0.738	0.659	0.660	0.659
average area compressibility (mN/m)^b	399 ± 5	407 ± 5	411 ± 7	389 ± 4	392 ± 6	391 ± 7
average tail order DPPC^c	0.634	0.626	0.639	0.533	0.534	0.535
average tail order DLiPC/DOPC^c	0.244	0.245	0.241	0.380	0.382	0.382
average bilayer thickness (nm)^c	4.071	4.075	4.061	4.191	4.190	4.190
CHOL flip-flop rate (10⁶ s^–1)^b	5.45 ± 0.08	0.0	0.0	1.77 ± 0.05	0.0	0.0

All errors are standard errors and were omitted if ≤0.002.

Averaged over the last 10 μs.

Averaged over the last 2 μs.

Table 1. Membrane Properties of the Ternary Mixtures DPPC/DLiPC/CHOL and DPPC/DOPC/CHOLa.