Table 4. Drug Loading Shown as the Amount of Drug Incorporated per Bead as Well as Drug Loading Presented as the Mass Percentagea,b.
| loaded beads | incorporated drug amount in one bead (mg) | drug amount percentage per one dry bead (%) |
|---|---|---|
| T_4_T3 | 0.072 ± 0.002 | 5.0 |
| T_4_T2 | 0.052 ± 0.002 | 4.2 |
| T_4_T1 | 0.049 ± 0.004 | 3.7 |
| L_20_T3 | 0.396 ± 0.032 | 27.3 |
| L_20_T2 | 0.333 ± 0.050 | 26.6 |
| L_20_T1 | 0.313 ± 0.052 | 23.3 |
| L_4_T3 | 0.118 ± 0.022 | 8.1 |
| L_4_T2 | 0.095 ± 0.036 | 7.6 |
| L_4_T1 | 0.065 ± 0.008 | 4.8 |
| R_20_T3 | 0.207 ± 0.005 | 14.3 |
| R_20_T2 | 0.163 ± 0.015 | 13.0 |
| R_20_T1 | 0.172 ± 0.038 | 12.7 |
| R_4_T3 | 0.081 ± 0.005 | 5.6 |
| R_4_T2 | 0.063 ± 0.002 | 5.1 |
| R_4_T1 | 0.068 ± 0.002 | 5.0 |
a
Average weights of a bead for T1, T2, and T3 beads are 1.35, 1.25, and 1.45 mg, respectively. T.4, Thp 4 mg/mL; L.20 and L.4, LiHCl 20 and 4 mg/mL; R.20 and R.4, RSP 20 and 4 mg/mL.
b
Reprinted from ref (86) with permission from Elsevier.