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. 2017 Sep 8;22(9):1505. doi: 10.3390/molecules22091505

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Hair regenerative effects of red ginseng oil (RGO) and its major compounds in the testosterone (TES)-induced androgenic alopecia C57BL/6 mouse models. The shaved-back skins of mice were daily treated with 0.5% TES for 1 h prior to topical application of 10% RGO, 1% LA, 1% SITOS, or 1% BICYCLO once a day for 28 days. Mice in the positive control group were treated with 0.5% TES and orally administered with FINAS (1 mg/kg) once a day for 28 days. The dorsal skins were photographed at day 0, 10, 14, 17, 21, and 28 (A). Hair re-growth efficacy score was measured as 0, 1, 2, 3, 4, and 5 in correspondence to 0%, 0–20%, 20–40%, 40–60%, 60–80%, and 80–100% of hair growth (B).

Hair regenerative effects of red ginseng oil (RGO) and its major compounds in the testosterone (TES)-induced androgenic alopecia C57BL/6 mouse models. The shaved-back skins of mice were daily treated with 0.5% TES for 1 h prior to topical application of 10% RGO, 1% LA, 1% SITOS, or 1% BICYCLO once a day for 28 days. Mice in the positive control group were treated with 0.5% TES and orally administered with FINAS (1 mg/kg) once a day for 28 days. The dorsal skins were photographed at day 0, 10, 14, 17, 21, and 28 (A). Hair re-growth efficacy score was measured as 0, 1, 2, 3, 4, and 5 in correspondence to 0%, 0–20%, 20–40%, 40–60%, 60–80%, and 80–100% of hair growth (B).