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. 2017 Sep 13;22(9):1533. doi: 10.3390/molecules22091533

Scheme 4.

Scheme 4

Synthesis of 2′′,2′′′-[6′-(4-sulfamoylphenylamino)-1′,3′,5′-triazine-2′,4′-diyl]-bis(azanediyl)diacetic acid 3. Reagents and conditions: 4-(4′,6′-dichloro-1′,3′,5′-triazin-2′-ylamino)-benzene-sulfonamide 1, glycine, NaOH, and H2O were refluxed for 24 h. Product yield: 65%.