Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Senescence-associated secretory phenotype (SASP) and tumorigenesis. Cellular senescence by multiple causes: (black) shows distinct phenotypes, including SASP (purple) that can induce anti-tumor (orange) or pro-tumor (sky-blue) development. DDR: DNA damage response, CDK: cyclin-dependent kinase, MMP2: matrix metalloproteinase 2, GM-CSF: granulocyte-macrophage colony-stimulating factor, HGF: hepatocyte growth factor.
