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. 2017 Oct 7;22(10):1669. doi: 10.3390/molecules22101669

Figure 8.

Figure 8

Effect of RA on plasma membrane GLUT levels and glucose uptake in GLUT-overexpressing cells. L6 GLUT4myc (A,C) or GLUT1myc (B,D) overexpressing cells were treated with 5 µM rosmarinic acid (RA) (4 h), 5 μg/mL rosemary extract (RE) (4 h), insulin (I) (100 nM, 0.5 h), or 2 mM metformin (MET) (4 h), followed by GLUT4 or GLUT1 plasma membrane transporter level measurements (A,B) or glucose uptake measurements (C,D). Results are mean ± SE of 5–7 independent experiments. *** p < 0.001 vs. control.