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. 2017 Sep 1;22(9):1457. doi: 10.3390/molecules22091457

Table 8.

MICs of Isoniazid-Nitrogen heterocyclic hydrazones against M.tb H37Rv.

Compound MW (g/mol) MIC (μg/mL)/(μM) LogP Cpd MW (g/mol) MIC (μg/mL)/(μM) LogP
2 215.21 0.03/0.14 −1.00 7 265.27 0.015/0.056 0.24
3 229.24 0.03/0.13 −1.37 8 264.28 0.06/0.23 0.86
4 265.27 0.06/0.23 1.38 9 343.18 0.125/0.36 1.69
5 265.27 0.03/0.11 −0.52 10 264.28 0.06/0.23 0.52
6 278.31 0.25/0.90 0.49 11 309.28 0.25/0.81 1.39
INH 137.14 0.05/0.36 −0.64