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Correlation between H. pylori mutations and CYP2C19 genetic polymorphism.
| CYP2C19 polymorphism (cases) | Mutation rates (%) and cases (n) | ||
|---|---|---|---|
| 23S rRNA | gyrA N87K | gyrA D91G/ D91N | |
| Hom-EMs (284) | 27.82 (79) | 19.01 (54) | 6.34 (18) |
| Het-EMs (343) | 30.90 (106) | 21.57 (74) | 9.91 (34) |
| PMs (64) | 17.19 (11) | 15.63 (10) | 6.25 (4) |
| P value | 0.079 | 0.479 | 0.224 |
Hom-EMs: homozygous extensive metabolizers; Het-EMs: heterozygous extensive metabolizers; PMs: poor metabolizers
