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. Author manuscript; available in PMC: 2018 Sep 24.
Published in final edited form as: J Clin Psychiatry. 2017 May;78(5):e545–e552. doi: 10.4088/JCP.16m11031

Table 2.

Individual Patients with PTSD Receiving Prescriptions for Each Anticonvulsant by Non-PTSD Indicationa

By Individual Indication

Anticonvulsant
Rank
Overall No Indication
Identified
Impulse Control
Disorders
Alcohol Use
Disorders
Bipolar &
Schizoaffective
Disorders
Restless Legs
Syndrome
Headache
Disorders
Pain Disorders Seizure
Disorders
1 Gabapentin
102,791
Gabapentin
4,605
Valproic Acid
2,464
Gabapentin
32,192
Valproic Acid
17,567
Gabapentin
2,650
Gabapentin
47,076
Gabapentin
92,459
Gabapentin
5,976
2 Valproic Acid
49,197
Valproic Acid
2,761
Gabapentin
2,127
Valproic Acid
19,128
Gabapentin
12,205
Valproic Acid
640
Valproic Acid
21,146
Valproic Acid
39,312
Valproic Acid
3,737
3 Topiramate
22,803
Lamotrigine
915
Lamotrigine
543
Topiramate
6,516
Lamotrigine
8,198
Topiramate
426
Topiramate
16,414
Topiramate
19,471
Levetiracetam
2,048
4 Lamotrigine
17,009
Topiramate
670
Topiramate
486
Lamotrigine
5,902
Topiramate
3,794
Lamotrigine
319
Lamotrigine
7,196
Lamotrigine
13,552
Topiramate
1,936
5 Carbamazepine
8,627
Carbamazepine
482
Carbamazepine
418
Carbamazepine
3,007
Carbamazepine
2,841
Pregabalin
207
Carbamazepine
3,794
Carbamazepine
6,973
Phenytoin
1,930
6 Pregabalin
4,748
Phenytoin
340
Phenytoin
108
Phenytoin
1,717
Oxcarbazepine
651
Carbamazepine
134
Pregabalin
3,056
Pregabalin
4,528
Lamotrigine
1,684
7 Phenytoin
4,631
Levetiracetam
143
Oxcarbazepine
102
Levetiracetam
1,253
Phenytoin
597
Levetiracetam
95
Levetiracetam
1,798
Phenytoin
3,574
Primidone
1,488
8 Levetiracetam
3,746
Primidone
116
Pregabalin
86
Pregabalin
1,129
Pregabalin
594
Primidone
94
Phenytoin
1,696
Levetiracetam
3,033
Carbamazepine
1,201
9 Primidone
2,637
Pregabalin
86
Levetiracetam
83
Primidone
613
Levetiracetam
513
Phenytoin
57
Primidone
804
Primidone
2,122
Pregabalin
431
10 Oxcarbazepine
1,482
Oxcarbazepine
65
Primidone
39
Oxcarbazepine
570
Primidone
331
Oxcarbazepine
25
Oxcarbazepine
722
Oxcarbazepine
1,204
Oxcarbazepine
262
11 Zonisamide
230
Tiagabine
19
Zonisamide
3
Tiagabine
59
Tiagabine
36
Zonisamide
6
Zonisamide
150
Zonisamide
190
Zonisamide
100
12 Tiagabine
194
Zonisamide
6
Tiagabine
2
Zonisamide
48
Zonisamide
31
Tiagabine
0
Tiagabine
83
Tiagabine
151
Tiagabine
22

Total 182,077 9,517 4,982 58,586 35,233 3,708 82,661 154,491 14,049
a

Note. All patients are included.

FDA approved indication 79.7% (145,155/182,077)

Add additional recommendations 90.0% (163,848/182,077)