Table 2.
Cytotoxic activity of M. splendens EO, α-bisabolol and trans-nerolidol on three cell lines after 48 h.
| Cell Line (IC50 µg/mL) 1 | |||
|---|---|---|---|
| A549 2 | MCF-7 3 | HaCaT 4 | |
| M. splendens EO | 100.99 ± 2.32 6d | 5.59 ± 0.13 6c | 21.58 ± 1.26 6c |
| α-bisabolol | 27.63 ± 2.01 6b | 1.24 ± 0.03 6a | 10.15 ± 0.35 6b |
| trans-nerolidol | 54.28 ± 2.39 6c | 40.97 ± 5.07 6d | 27.76 ± 2.76 6d |
| doxorubicin 5 | 0.90 ± 0.01 6a | 2.10 ± 0.42 6b | 0.40 ± 0.01 6a |
1 IC50: compound concentrations that affords a 50% cell growth decrease after 48 h. IC50 are the averages of triplicate experiments and represented as mean ± standard deviation; 2 Adenocarcinoma cell line; 3 Breast adenocarcinoma cell line; 4 Keratinocytes cell line; 5 Doxorubicin was used as positive control; 6 Data are presented as mean ± SD, n = 3. Means in each column followed by different letter are significantly different (p < 0.05).