AD |
Alzheimer’s disease |
FDA |
Food and Drug Administration |
AchE |
acetylcholinesterase |
NMDAR |
N-methyl-d-aspartate receptor |
MAPK |
mitogen-activated protein kinase |
ROS |
reactive oxygen species |
JNK |
c-jun N-terminal kinase |
ERK |
extracellular signal-regulated kinase |
TNF-α |
tumor necrosis factor-α |
IL-1 |
interleukin-1 |
LPS |
lipopolysaccharide |
ATP |
adenosine triphosphate |
CNS |
central nervous systems |
Aβ |
amyloid-β |
NFTs |
neurofibrillary tangles |
APP |
amyloid precursor protein |
PS |
presenilin |
NO |
nitric oxide |
NSAIDs |
nonsteroidal anti-inflammatory drugs |
iNOS |
inducible nitric oxide synthase |
NF-kB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
LTP |
long-term potentiation |
LTD |
long-term depression |
mGluR |
metabotropic glutamate receptor |
AMPAR |
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor |
BBB |
blood-brain barrier |