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. 2017 Aug 1;22(8):1281. doi: 10.3390/molecules22081281
ADCs Antibody-drug conjugates
ALCL Anaplastic large-cell lymphoma
AML Acute myelogenous leukemia
BCMA B-cell maturation antigen
CA9 Carbonic anhydrase IX
CEA Carcinoembryonic antigen
CLL Chronic lymphocytic leukemia
DAR Drug-to-antibody ratio
DLBCL Diffuse large B cell lymphoma
DTT Dithiothreitol
EDNRB Endothelin receptor type B
EGFR Epidermal growth factor receptor
ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
EphA2 Ephrin type-A receptor 2
EphB2 Ephrin type-B receptor 2
FDA Food and Drug Administration
GCC Guanyl cyclase C
GPNMB Transmembrane glycoprotein NMB
GTP Guanosine triphosphate
HER2 Human epidermal growth factor receptor 2
HL Hodgkin’s lymphoma
IgG Immunoglobulin G
LBCL Large B-cell lymphoma
LY6E Lymphocyte antigen 6 complex
mAb Monoclonal antibody
MBC Metastatic breast cancer
MC Maleimidocaproyl
MCC 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate
MDR Multiple-drug resistant
MDR1 Multidrug resistance protein 1
MM Multiple myeloma
MMAE Monomethyl auristatin E
MMAF Monomethyl auristatin F
MTD Maximum tolerated dose
MUC16 Mucin 16
NHL Non-Hodgkin’s lymphoma
NSCLC Non-small cell lung cancer
PEG Polyethylene glycol
PK/PD Pharmacokinetic/pharmacodynamics
PSMA Prostate specific membrane antigen
RCC Renal cell carcinoma
SAR Structure-activity relationship
SCLC Small-cell lung cancer
SLITRK6 SLIT and NTRK-like protein 6
SMCC Succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate
SPDB N-Succinimidyl-4-(2-pyridyldithio)butanoate
SPP N-Succinimidyl 4-(2-pyridyldithio) pentanoate
sSPDB Sulfo-SPDB
STEAP1 Six transmembrane epithelial Antigen of prostate 1
TAG-72 Tumor-associated glycoprotein-72
vc Valine-citrulline