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Schematic view of main chemical modifications (d-amino acids, Glycosylation, PEGylation, etc.) introduced in peptide-based radiopharmaceuticals designed for imaging or radiotherapy. The modified peptide moiety, covalently bounded to the chelator through a linker inserted as spacer, acts as carrier to specific receptor. (A) Linear targeting peptide; (B) Multimeric targeting peptide; (C) Cyclic peptide.
