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In vivo acute oral toxicity study and gross behavioral studies of the synthesized compounds 4e and 4k.
| Observation | Compound | |
|---|---|---|
| 4e | 4k | |
| Toxicity | N | N |
| Deaths | N | N |
| Eye Lacrimation | N | N |
| Salivation | N | N |
| Diarrhea | N | N |
| Respiration Problems | N | N |
| Straub Tail | N | N |
| Pilo Erection | N | N |
| Convulsions | N | N |
| Normal Motor Activity | Y | Y |
| Stereotypy | N | N |
| Tremors | N | N |
| Sedation | N | N |
| Hypnosis | N | N |
| Muscle Spasms | N | N |
N: no; Y: yes.
