Table. Cases of Plasmodium knowlesi infections reported in Germany, 2012–2017.
Case ID | Date of admission | Age in years | Sex | Level of care | RDT | Smear parasitaemiaa | Nuclear amplification techniques | Treatment |
---|---|---|---|---|---|---|---|---|
1 | January 2012 | 54 | Male | IPD | Not done | 0.01% | Sequencing positiveb | Atovaquone/proguanil |
2 | January 2013 | 55 | Female | IPD | BinaxNOW, pan-aldolase (T2 band) positive | 0.2% | PCR positivec | Artesunate followed by Artemether/lumefantrine |
3 | December 2013 | 73 | Male | ICU | BinaxNOW negative | 3% | PCR positivec | Quinine/doxycycline |
4 | December 2014 | 52 | Female | IPD | BinaxNOW negative | 1% | PCR positivec | Artemether/lumefantrine |
5 | February 2015 | 42 | Male | IPD | BinaxNOW negative | 0.02% | PCR positivec | Atovaquone/proguanil |
6 | January 2017 | 45 | Male | OPD | BinaxNOW negative | 0.0002% | PCR positivec | Atovaquone/proguanil |
ICU: intensive care unit; IPD: in-patient department; OPD: out-patient department; RDT: rapid diagnostic test.
a Percentages of infected erythrocytes are presented.
b Sequencing of small subunit ribosomal RNA, Basic Local Alignment Search Tool analysis of the obtained sequence, yields a 96% match with the respective P. knowlesi sequence.
c A PCR with primers specific for P. knowlesi was conducted.